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January 2007

Volume 11, Issue 1


Pathology Service Enhancement
By Brian A. Schaefer, D. Phil

Moving Expertise from the Laboratory to the Point of Care

Throughout the last decade Drs. Smith and McNeely have conducted research aimed at improving clinical laboratory utilisation. This research has produced a technology that has been shown to have dramatic implications for clinical laboratories, patient care and healthcare economics


Evaluation Of Cartridge-Saturation versus OTC Drug Interference
By Jean-Nicholas Mess, Audrey Tousignant, Malika Madi, Troy Bradley and Fabio Garofolo

When Using Cation-Exchange SPE for Bioanalytical Method Development in LC-MS/MS

Solid-Phase-Extraction (SPE) is a powerful tool for extraction of drugs from biological samples. It is reliable and efficient and it can be easily
automated for high-throughput bioanalysis. SPE is particularly suitable in LC-MS/MS detection when high sensitivity is required because it leads to a clean extraction with minimized ionization suppression.